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Volume 1 – Issue 2 – 2020

Synthesis, Characterization and Evaluation Of In Vitro Antioxidant Activity of Cobalt Nanoparticles: Concentration and Stability Dependent Approach

Vijayta Gupta1*, Pawan K.Verma2, Annuradha Gupta3, Vinay Kant4, Meena Sharma1

1Department of Chemistry, University of Jammu (J&K)-180006, (INDIA)
2Division of Pharmacology & Toxicology, SKUAST-Jammu, (INDIA)
3Department of Physics, University of Jammu, (INDIA)
4Department of Veterinary Pharmacology & Toxicology, IVRI, Izatnagar, UP, (INDIA)

PAGE NO: 84-90


The present investigation was aimed to evaluate the in vitro antioxidant potential of cobalt (Co) nanoparticles. Co nanoparticles were synthesized by reducing cobalt salt using hydrazine hydrate and its suspensions of different concentrations were prepared for further evaluations. The average size of synthesized Co nanoparticles was in nano range and they were spherical in shape. The Co nanoparticles showed the inhibition of the different in-vitro free radicals i.e. ABTS, DPPH, superoxide anion and H2O2 radicals in a concentration dependent manner on different days. The radicals scavenging activity of Co nano-suspensions were marked reduced on its storage for 30 and 60 days. In conclusion, the potentials of Co nanoparticles as a synthetic antioxidant may be exploited to counter the problems associated with free radicals in different fields of Veterinary sciences, Medical sciences, agriculture, food sciences, etc.