Synthesis, Characterization and Evaluation Of In Vitro Antioxidant Activity of Cobalt Nanoparticles: Concentration and Stability Dependent Approach

Vijayta Gupta^1*, Pawan K.Verma², Annuradha Gupta³, Vinay Kant⁴, Meena Sharma¹

¹Department of Chemistry, University of Jammu (J&K)-180006, (INDIA)
²Division of Pharmacology & Toxicology, SKUAST-Jammu, (INDIA)
³Department of Physics, University of Jammu, (INDIA)
⁴Department of Veterinary Pharmacology & Toxicology, IVRI, Izatnagar, UP, (INDIA)

PAGE NO: 84-90

ABSTRACT – DOI : https://dx.doi.org/10.47204/EMSR.1.2.2020.084-090

The present investigation was aimed to evaluate the in vitro antioxidant potential of cobalt (Co) nanoparticles. Co nanoparticles were synthesized by reducing cobalt salt using hydrazine hydrate and its suspensions of different concentrations were prepared for further evaluations. The average size of synthesized Co nanoparticles was in nano range and they were spherical in shape. The Co nanoparticles showed the inhibition of the different in-vitro free radicals i.e. ABTS, DPPH, superoxide anion and H₂O₂ radicals in a concentration dependent manner on different days. The radicals scavenging activity of Co nano-suspensions were marked reduced on its storage for 30 and 60 days. In conclusion, the potentials of Co nanoparticles as a synthetic antioxidant may be exploited to counter the problems associated with free radicals in different fields of Veterinary sciences, Medical sciences, agriculture, food sciences, etc.